C2cd3^em1Brgm
Endonuclease-mediated Allele Detail

Summary

• Symbol: C2cd3^em1Brgm
• Name: C2 calcium-dependent domain containing 3; endonuclease-mediated mutation 1, Samantha A Brugmann
• MGI ID: MGI:6887610
• Synonyms: C2cd3^ex2
• Gene: C2cd3 Location: Chr7:100021440-100119359 bp, + strand Genetic Position: Chr7, 54.35 cM
• Alliance: C2cd3^em1Brgm page
• IMPC: C2cd3 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 8 bp. (J:308674)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C2cd3 Mutation: 101 strains or lines available

References

• Original: J:308674 Chang CF, et al., Centriolar Protein C2cd3 Is Required for Craniofacial Development. Front Cell Dev Biol. 2021;9:647391
• All: 1 reference(s)