Or12d17^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Or12d17^em1Cya
• Name: olfactory receptor family 12 subfamily D member 17; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6887709
• Synonyms: Olfr109^-, Olfr109^em1cyagen, Or12d17^em1Cgen
• Gene: Or12d17 Location: Chr17:37777099-37778043 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Or12d17^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeted exon 1 for deletion and generated a 562 bp deletion. (J:321591)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or12d17 Mutation: 18 strains or lines available

References

• Original: J:321591 Cheng J, et al., Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism. Cell Metab. 2022 Feb 1;34(2):240-255.e10
• All: 1 reference(s)