Mios^tm1Pfw
Targeted Allele Detail

Summary

• Symbol: Mios^tm1Pfw
• Name: meiosis regulator for oocyte development; targeted mutation 1, Paul Worley
• MGI ID: MGI:6887905
• Synonyms: Mios f
• Gene: Mios Location: Chr6:8209222-8236274 bp, + strand Genetic Position: Chr6, 3.51 cM
• Alliance: Mios^tm1Pfw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:320720
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeted mutation floxed exons 3 and 4 and inserted a neomycin resistance cassette. (J:320720)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mios Mutation: 41 strains or lines available

References

• Original: J:320720 Yu Z, et al., GATOR2 complex-mediated amino acid signaling regulates brain myelination. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2110917119
• All: 1 reference(s)