Rad51ap2^em2Qsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rad51ap2^em2Qsh
• Name: RAD51 associated protein 2; endonuclease-mediated mutation 2, Qinghua Shi
• MGI ID: MGI:6888020
• Synonyms: Rad51ap2^deltaC689, RAD51AP2^deltaSRPI
• Gene: Rad51ap2 Location: Chr12:11506080-11512929 bp, + strand Genetic Position: Chr12, 5.58 cM
• Alliance: Rad51ap2^em2Qsh page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 created a truncation at C689 (p.S288Pfs*4). (J:321708)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rad51ap2 Mutation: 58 strains or lines available

References

• Original: J:321708 Ma H, et al., RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes. Sci Adv. 2022 Jan 14;8(2):eabk1789
• All: 1 reference(s)