Ptch2^tm1Bjw
Targeted Allele Detail

Summary

• Symbol: Ptch2^tm1Bjw
• Name: patched 2; targeted mutation 1, Brandon J. Wainwright
• MGI ID: MGI:7256321
• Synonyms: Ptch2^lacZ
• Gene: Ptch2 Location: Chr4:116953272-116973298 bp, + strand Genetic Position: Chr4, 53.41 cM, cytoband C-D
• Alliance: Ptch2^tm1Bjw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210838
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into exon 2 an IRES, lacZ reporter gene, and floxed neomycin resistance cassette (J:210838)

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptch2 Mutation: 47 strains or lines available

References

• Original: J:210838 Adolphe C, et al., Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation. J Invest Dermatol. 2014 Jul;134(7):1981-90
• All: 2 reference(s)