H3c6^em1Sjes
Endonuclease-mediated Allele Detail

Summary

• Symbol: H3c6^em1Sjes
• Name: H3 clustered histone 6; endonuclease-mediated mutation 1, Sebastian Jessberger
• MGI ID: MGI:7256441
• Synonyms: H3.1-iCOUNT, H3c6^{tm1(mCherry,GFP)Sjes}
• Gene: H3c6 Location: Chr13:23745708-23746543 bp, - strand Genetic Position: Chr13, 9.79 cM, cytoband A2-A3
• Alliance: H3c6^em1Sjes page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted a recombination-induced tag exchange (RITE) containing a loxP site, mCherry reporter gene, T2A, neomycin resistance cassette, loxP site, and EGFP reporter gene. (J:321942)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any H3c6 Mutation: 8 strains or lines available

References

• Original: J:321942 Denoth-Lippuner A, et al., Visualization of individual cell division history in complex tissues using iCOUNT. Cell Stem Cell. 2021 Nov 4;28(11):2020-2034.e12
• All: 1 reference(s)