Drg1^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Drg1^em1(IMPC)Tcp
• Name: developmentally regulated GTP binding protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:7256883
• Gene: Drg1 Location: Chr11:3199907-3221882 bp, - strand Genetic Position: Chr11, 2.23 cM
• Alliance: Drg1^em1(IMPC)Tcp page
• IMPC: Drg1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted 971-bp (Chr11:3262343-3263313_insA; GRCm38). This deletion leads to a frameshift and premature stop codon within exon 4. (J:322048, J:344816)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Drg1 Mutation: 25 strains or lines available

References

• Original: J:322048 The Centre for Phenogenomics, Direct Data Submission for The Centre for Phenogenomics Alleles. MGI Direct Data Submission. 2022
• All: 4 reference(s)