Pxmp4^em1Jwjk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pxmp4^em1Jwjk
• Name: peroxisomal membrane protein 4; endonuclease-mediated mutation 1, Johan W Jonker
• MGI ID: MGI:7258107
• Gene: Pxmp4 Location: Chr2:154427678-154445592 bp, - strand Genetic Position: Chr2, 76.79 cM, cytoband H2
• Alliance: Pxmp4^em1Jwjk page

Mutation origin

• Strain of Origin: FVB

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted 19 bp. (J:322224)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pxmp4 Mutation: 15 strains or lines available

References

• Original: J:322224 Blankestijn M, et al., Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism. Sci Rep. 2022 Feb 15;12(1):2512
• All: 1 reference(s)