Eya2^tm1Px
Targeted Allele Detail

Summary

• Symbol: Eya2^tm1Px
• Name: EYA transcriptional coactivator and phosphatase 2; targeted mutation 1, Pin-Xian Xu
• MGI ID: MGI:7260239
• Gene: Eya2 Location: Chr2:165436952-165613647 bp, + strand Genetic Position: Chr2, 85.83 cM
• Alliance: Eya2^tm1Px page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:311538
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting cassette replacing exon 11 encoding 55 resides of the conserved 217 amino acid ED domain. (J:311538)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eya2 Mutation: 37 strains or lines available

References

• Original: J:311538 Zhang T, et al., Eya2 expression during mouse embryonic development revealed by Eya2(lacZ) knockin reporter and homozygous mice show mild hearing loss. Dev Dyn. 2021 Oct;250(10):1450-1462
• All: 2 reference(s)