Pde7b^tm1Pfi
Targeted Allele Detail

Summary

• Symbol: Pde7b^tm1Pfi
• Name: phosphodiesterase 7B; targeted mutation 1, Pfizer, Ltd
• MGI ID: MGI:7261163
• Gene: Pde7b Location: Chr10:20273750-20600824 bp, - strand Genetic Position: Chr10, 9.75 cM, cytoband A3
• Alliance: Pde7b^tm1Pfi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322967
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• The targeting construct replaced 2,380bp with a lacZ/neomycin resistance cassette. (J:322967)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pde7b Mutation: 32 strains or lines available

References

• Original: J:322967 Chevalier E, et al., Lack of involvement of type 7 phosphodiesterase in an experimental model of asthma. Eur Respir J. 2012 Mar;39(3):582-8
• All: 1 reference(s)