Cdk19^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdk19^em1Smoc
• Name: cyclin dependent kinase 19; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7261165
• Gene: Cdk19 Location: Chr10:40225283-40359814 bp, + strand Genetic Position: Chr10, 21.94 cM
• Alliance: Cdk19^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 2 produced a null allele. (J:322947)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk19 Mutation: 96 strains or lines available

References

• Original: J:322947 Zhang Z, et al., CDK19 regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells by suppressing p53-mediated transcription of p21. Leukemia. 2022 Feb 2
• All: 1 reference(s)