4930522H14Rik^em1Kher
Endonuclease-mediated Allele Detail

Summary

• Symbol: 4930522H14Rik^em1Kher
• Name: RIKEN cDNA 4930522H14 gene; endonuclease-mediated mutation 1, Zine-Eddine Kherraf
• MGI ID: MGI:7261402
• Synonyms: 4930522H14Rik^-
• Gene: 4930522H14Rik Location: Chr4:109362534-109388494 bp, - strand Genetic Position: Chr4, 51.29 cM, cytoband C7
• Alliance: 4930522H14Rik^em1Kher page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mediated recombination created a 77bp frameshift deletion in exon 2 (c.41-117del). (J:323102)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 4930522H14Rik Mutation: 15 strains or lines available

References

• Original: J:323102 Cazin C, et al., Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B. Cells. 2021 Dec 30;11(1)
• All: 1 reference(s)