Cct6b^em1Kher
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cct6b^em1Kher
• Name: chaperonin containing TCP1 subunit 6B; endonuclease-mediated mutation 1, Zine-Eddine Kherraf
• MGI ID: MGI:7261404
• Synonyms: Cct6b^-
• Gene: Cct6b Location: Chr11:82610076-82655147 bp, - strand Genetic Position: Chr11, 50.18 cM, cytoband B5
• Alliance: Cct6b^em1Kher page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created a 155bp frameshift deletion in exon 4(c.354-505del). (J:323102)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cct6b Mutation: 22 strains or lines available

References

• Original: J:323102 Cazin C, et al., Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B. Cells. 2021 Dec 30;11(1)
• All: 1 reference(s)