Clec2htm1.1Apma
Targeted Allele Detail
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Symbol: |
Clec2htm1.1Apma |
Name: |
C-type lectin domain family 2, member h; targeted mutation 1.1, Andrew P Makrigiannis |
MGI ID: |
MGI:7262867 |
Synonyms: |
Clr-f- |
Gene: |
Clec2h Location: Chr6:128639348-128654337 bp, + strand Genetic Position: Chr6, 63.07 cM, cytoband F3
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Alliance: |
Clec2htm1.1Apma page
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Germline Transmission: |
Earliest citation of germline transmission:
J:322835
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A PGK-neomycin selection cassette flanked by loxP sites replaced exons 3 and 4 and part of exon 5. The neomycin cassette was removed via flp-mediated recombination. RT-PCR conformed the complete loss of transcript and immunofluorescent labeling of the kidney and small intestine confirmed the absence of protein. In addition, protein expression of NKRP1G, which lies in apposition to this gene, is not affected.
(J:322835)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Clec2h Mutation: |
15 strains or lines available
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Original: |
J:322835 Zein HS, et al., Clr-f expression regulates kidney immune and metabolic homeostasis. Sci Rep. 2022 Mar 22;12(1):4834 |
All: |
1 reference(s) |
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