Cep20^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cep20^{tm1.1(KOMP)Vlcg}
• Name: centrosomal protein 20; targeted mutation 1.1, Velocigene
• MGI ID: MGI:7263004
• Synonyms: For20^-
• Gene: Cep20 Location: Chr16:14117108-14135269 bp, - strand Genetic Position: Chr16, 9.74 cM, cytoband B1
• Alliance: Cep20^{tm1.1(KOMP)Vlcg} page
• IMPC: Cep20 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:308526
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 17212bp between positions 14117971-14135182 of Chromosome 16 (Build GRCm39). This includes part of exon 1, exons 2 to 4, and part of exon 5. Subsequent cre-mediated excision deleted the neomycin selection cassette. (J:308526)

Expression

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cep20 Mutation: 24 strains or lines available

References

• Original: J:308526 Xu Z, et al., Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects. FEBS Lett. 2021 May;595(10):1462-1472
• All: 1 reference(s)