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Acox2em1Jynz
Endonuclease-mediated Allele Detail
Summary
Symbol: Acox2em1Jynz
Name: acyl-Coenzyme A oxidase 2, branched chain; endonuclease-mediated mutation 1, Jian-Yuan Zhao
MGI ID: MGI:7263204
Gene: Acox2  Location: Chr14:14210420-14244262 bp, + strand  Genetic Position: Chr14, 4.77 cM, cytoband A1
Alliance: Acox2em1Jynz page
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology generated a deletion of 15146bp spanning exon 3 to exon 13. (J:323193)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acox2 Mutation:  40 strains or lines available
References
Original:  J:323193 Zhang Y, et al., Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice. Cell Death Dis. 2022 Mar 29;13(3):279
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory