Amdhd2^em#Msde
Endonuclease-mediated Allele Detail

Summary

• Symbol: Amdhd2^em#Msde
• Name: amidohydrolase domain containing 2; endonuclease-mediated mutation, Martin S Denzel
• MGI ID: MGI:7276144
• Gene: Amdhd2 Location: Chr17:24374807-24382740 bp, - strand Genetic Position: Chr17, 12.28 cM
• Alliance: Amdhd2^em#Msde page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology targeted exon 4. Four lines were generated: line 1, 3, and 4 with complete exon 4 deletion and line 2 with the first 4 bp of exon 4 deleted. This record represents pooled data of the four lines generated or data where the line number is not specified. (J:324170)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amdhd2 Mutation: 22 strains or lines available

References

• Original: J:324170 Kroef V, et al., GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife. 2022 Mar 1;11:e69223
• All: 1 reference(s)