Calb1^{tm1.1(cre)Arte}
Targeted Allele Detail

Summary

• Symbol: Calb1^{tm1.1(cre)Arte}
• Name: calbindin 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:7280721
• Synonyms: CB^cre
• Gene: Calb1 Location: Chr4:15881264-15906709 bp, + strand Genetic Position: Chr4, 6.66 cM
• Alliance: Calb1^{tm1.1(cre)Arte} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256710
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Calb1^{tm1.1(cre)Arte} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Calb1 (MGI:88248)

• Mutation details: A cre expression cassette followed by FRT flanked Puro selection cassette was inserted immediately after the start codon ATG of the Calb1 gene replacing most of the exon 1. The puromycin selection cassette was removed by breeding to FLP deleter mice. (J:256710)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Calb1 (mouse) Summary of all recombinase alleles driven by Calb1. Comparative matrix view of recombinase activities Alliance mouse Calb1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Calb1 Mutation: 28 strains or lines available

References

• Original: J:256710 Fuchs EC, et al., Local and Distant Input Controlling Excitation in Layer II of the Medial Entorhinal Cortex. Neuron. 2016 Jan 6;89(1):194-208
• All: 1 reference(s)