Ppp4c^em1Qys
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp4c^em1Qys
• Name: protein phosphatase 4, catalytic subunit; endonuclease-mediated mutation 1, Qing-Yuan Sun
• MGI ID: MGI:7280773
• Synonyms: Ppp4c^flox
• Gene: Ppp4c Location: Chr7:126385038-126391668 bp, - strand Genetic Position: Chr7, 69.25 cM
• Alliance: Ppp4c^em1Qys page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology flanked exon 3 with loxP sites. (J:309155)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp4c Mutation: 41 strains or lines available

References

• Original: J:309155 Han F, et al., Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice. Mol Hum Reprod. 2021 Jan 22;27(1)
• All: 1 reference(s)