Myh11^tm1.2Ccai
Targeted Allele Detail

Summary

• Symbol: Myh11^tm1.2Ccai
• Name: myosin, heavy polypeptide 11, smooth muscle; targeted mutation 1.2, Chen-Leng Cai
• MGI ID: MGI:7281109
• Synonyms: Myh11^H2B-GFP
• Gene: Myh11 Location: Chr16:14012392-14109227 bp, - strand Genetic Position: Chr16, 9.71 cM
• Alliance: Myh11^tm1.2Ccai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319644
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A loxP flanked n-LacZ gene, H2G-GFP gene, and FRT flanked neo cassette were inserted 6 bp upstream of the start codon. Flp mediated recombination removed the neo cassette. Cre-mediated recombination removed the lacZ reporter gene. (J:319644)

Expression

In Mice Carrying this Mutation:

99 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myh11 Mutation: 94 strains or lines available

References

• Original: J:319644 Ruan J, et al., Novel Myh11 Dual Reporter Mouse Model Provides Definitive Labeling and Identification of Smooth Muscle Cells-Brief Report. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):815-821
• All: 1 reference(s)