Or2l13b^em1Scjc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Or2l13b^em1Scjc
• Name: olfactory receptor family 2 subfamily L member 13B; endonuclease-mediated mutation 1, Scott J Cameron
• MGI ID: MGI:7281119
• Synonyms: olfr168^-
• Gene: Or2l13b Location: Chr16:19348730-19349668 bp, - strand Genetic Position: Chr16, 12.09 cM
• Alliance: Or2l13b^em1Scjc page

Mutation origin

• Strain of Origin: FVB/NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated an 18 bp deletion (AAATGTCACTTGACTGTG). Immunoblotting-washed murine platelet lysate confirmed the absence of protein. (J:324598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or2l13b Mutation: 22 strains or lines available

References

• Original: J:324598 Morrell CN, et al., Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms. J Clin Invest. 2022 May 2;132(9):e152373
• All: 1 reference(s)