Trim69^em1Jsha
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim69^em1Jsha
• Name: tripartite motif-containing 69; endonuclease-mediated mutation 1, Jiahao Sha
• MGI ID: MGI:7284271
• Synonyms: Trim69^-
• Gene: Trim69 Location: Chr2:121991189-122009503 bp, + strand Genetic Position: Chr2, 60.55 cM
• Alliance: Trim69^em1Jsha page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 gene editing technology was used to generate an 8 bp deletion in exon 2. Western blot analysis confirmed the absence of protein expression in the testes of homozygous mutant mice. (J:324143)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim69 Mutation: 29 strains or lines available

References

• Original: J:324143 He X, et al., The testis-specifically expressed gene Trim69 is not essential for fertility in mice. J Biomed Res. 2020 Aug 21;35(1):47-60
• All: 1 reference(s)