Zmym3^em1Hncs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zmym3^em1Hncs
• Name: zinc finger, MYM-type 3; endonuclease-mediated mutation 1, Chunsheng Han
• MGI ID: MGI:7287466
• Synonyms: Zmym3^a2
• Gene: Zmym3 Location: ChrX:100447990-100464455 bp, - strand Genetic Position: ChrX, 44.1 cM, cytoband C-D
• Alliance: Zmym3^em1Hncs page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 produced a 106 bp deletion. (J:324172)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zmym3 Mutation: 5 strains or lines available

References

• Original: J:324172 Hu X, et al., Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic metaphase with defects in spindle assembly checkpoint. Cell Death Dis. 2017 Jun 29;8(6):e2910
• All: 1 reference(s)