Tfap2etm1Mos
Targeted Allele Detail
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Symbol: |
Tfap2etm1Mos |
Name: |
transcription factor AP-2, epsilon; targeted mutation 1, Markus Moser |
MGI ID: |
MGI:7287853 |
Gene: |
Tfap2e Location: Chr4:126609799-126630033 bp, - strand Genetic Position: Chr4, 60.91 cM
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Alliance: |
Tfap2etm1Mos page
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Germline Transmission: |
Earliest citation of germline transmission:
J:317046
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Insertion
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Mutation details: A neomycin DNA construct containing a stop codon was inserted into the second exon of the gene. This results in a premature termination of the translation process and a complete absence of functional encoded protein in homozygous mice.
(J:317046)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tfap2e Mutation: |
10 strains or lines available
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Original: |
J:317046 Niebler S, et al., Activating enhancer binding protein 2 epsilon (AP-2epsilon)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development. Arthritis Res Ther. 2015 May 12;17:119 |
All: |
2 reference(s) |
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