Dyrk1a^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Dyrk1a^tm1Smoc
• Name: dual-specificity tyrosine phosphorylation regulated kinase 1a; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7289422
• Synonyms: Dyrk1a^{tm1(flox)Smoc}
• Gene: Dyrk1a Location: Chr16:94370869-94496376 bp, + strand Genetic Position: Chr16, 55.3 cM
• Alliance: Dyrk1a^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: These mice carry loxP sites flanking exon 5-6 of Dyrk1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dyrk1a gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dyrk1a Mutation: 114 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)