H2-Eab-em2Smoc
Endonuclease-mediated Allele Detail
|
Symbol: |
H2-Eab-em2Smoc |
Name: |
histocompatibility 2, class II antigen E alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:7290147 |
Synonyms: |
H2-Eaem2Smoc |
Gene: |
H2-Ea Location: Chr17:34560926-34563618 bp, - strand Genetic Position: Chr17, 17.98 cM
|
Alliance: |
H2-Eab-em2Smoc page
|
|
|
Allele Type: |
|
Endonuclease-mediated (Null/knockout) |
Mutation: |
|
Intragenic deletion
|
|
|
Mutation details: All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1 H2-AA H2-Eb1 H2-Eb2 H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.
(J:238766)
|
Inheritance: |
|
Not Specified |
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any H2-Ea Mutation: |
7 strains or lines available
|
|
Original: |
J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017; |
All: |
1 reference(s) |
|