Il13^{em1(icre)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il13^{em1(icre)Smoc}
• Name: interleukin 13; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7290424
• Synonyms: Il13^{em1(IRES-iCre)Smoc}
• Gene: Il13 Location: Chr11:53522151-53525529 bp, - strand Genetic Position: Chr11, 31.98 cM
• Alliance: Il13^{em1(icre)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Il13^{em1(icre)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Il13 (MGI:96541)

• Mutation details: A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process. (J:238766)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Il13 (mouse) Summary of all recombinase alleles driven by Il13. Alliance mouse Il13 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il13 Mutation: 30 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)