Sost^{em2(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sost^{em2(cre/ERT2)Smoc}
• Name: sclerostin; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7292534
• Synonyms: Sost^{em(CreERT2-Wpre-pA)Smoc}
• Gene: Sost Location: Chr11:101853284-101857841 bp, - strand Genetic Position: Chr11, 65.48 cM, cytoband D
• Alliance: Sost^{em2(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Sost^{em2(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sost (MGI:1921749)

• CreERT2-Wpre-pA expression cassette was knocked into the Sost gene . (J:238766)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sost (mouse) Summary of all recombinase alleles driven by Sost. Alliance mouse Sost gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sost Mutation: 35 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)