Tnfrsf1aem2Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Tnfrsf1aem2Smoc |
Name: |
tumor necrosis factor receptor superfamily, member 1a; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:7292882 |
Gene: |
Tnfrsf1a Location: Chr6:125326686-125339446 bp, + strand Genetic Position: Chr6, 59.32 cM
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Alliance: |
Tnfrsf1aem2Smoc page
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).
(J:238766)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tnfrsf1a Mutation: |
52 strains or lines available
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Original: |
J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017; |
All: |
2 reference(s) |
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