Dgkh^em1Mjz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dgkh^em1Mjz
• Name: diacylglycerol kinase, eta; endonuclease-mediated mutation 1, Mark J Zylka
• MGI ID: MGI:7294352
• Gene: Dgkh Location: Chr14:78796789-78970169 bp, - strand Genetic Position: Chr14, 41.56 cM
• Alliance: Dgkh^em1Mjz page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 9 inserted a 22 bp cassette containing a STOP codon (J:325758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dgkh Mutation: 57 strains or lines available

References

• Original: J:325758 Bartsch VB, et al., Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice. Genes Brain Behav. 2020 Mar;19(3):e12570
• All: 1 reference(s)