Cep78^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cep78^em2Gpt
• Name: centrosomal protein 78; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7296812
• Synonyms: Cep78^em2Cd1920
• Gene: Cep78 Location: Chr19:15933137-15962353 bp, - strand Genetic Position: Chr19, 10.89 cM
• Alliance: Cep78^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon2 through 4 (del1920). (J:333155)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cep78 Mutation: 43 strains or lines available

References

• Original: J:333155 Zhang X, et al., Loss-of-function mutations in CEP78 cause male infertility in humans and mice. Sci Adv. 2022 Oct 7;8(40):eabn0968
• All: 1 reference(s)