Igs2^{em42(DBH-icre)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igs2^{em42(DBH-icre)Gpt}
• Name: intergenic site 2; endonuclease-mediated mutation 42, GemPharmatech Co., Ltd
• MGI ID: MGI:7300655
• Synonyms: H11^{em1-hDBH-icre}
• Gene: Igs2 Location: Chr11:3195460-3195497 bp Genetic Position: Chr11, Syntenic
• Alliance: Igs2^{em42(DBH-icre)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Igs2^{em42(DBH-icre)Gpt} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  DBH (1621)

  Dbh	(MGI:94864)

• Mutation details: CRISPR-targeting introduced the human gene promoter driving expression of an improved cre recombinase gene (icre). (J:293217)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	DBH (human) Summary of all recombinase alleles driven by DBH. Alliance human DBH gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs2 Mutation: 72 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)