Kras^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kras^em1Gpt
• Name: Kirsten rat sarcoma viral oncogene homolog; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7301371
• Synonyms: Kras^{em1Cin(loxP-stop-loxP-G12D)}
• Gene: Kras Location: Chr6:145162425-145195965 bp, - strand Genetic Position: Chr6, 77.37 cM, cytoband G2
• Alliance: Kras^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting inserted a loxP site flanked STOP cassette into intron 1 and a mutation in exon 2 that changes glycine codon 12 to aspartic acid (p.G12D). (J:293217)
• Inheritance: Not Specified

Tumor Data

List all tumor models in MMHCdb carrying Kras^em1Gpt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kras Mutation: 84 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 3 reference(s)