Lgr5^{em1(cre/ERT2)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lgr5^{em1(cre/ERT2)Gpt}
• Name: leucine rich repeat containing G protein coupled receptor 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7301624
• Synonyms: Lgr5^em1-cre/ERT2
• Gene: Lgr5 Location: Chr10:115286219-115423685 bp, - strand Genetic Position: Chr10, 63.51 cM
• Alliance: Lgr5^{em1(cre/ERT2)Gpt} page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Lgr5^{em1(cre/ERT2)Gpt} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lgr5 (MGI:1341817)

• CRISPR-targeting introduced an inducible recombinase gene fusion (cre/ERT2). (J:293217)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lgr5 (mouse) Summary of all recombinase alleles driven by Lgr5. Alliance mouse Lgr5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lgr5 Mutation: 58 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 3 reference(s)