Nkx2-5^em1(icre)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nkx2-5^em1(icre)Gpt
• Name: NK2 homeobox 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7303047
• Synonyms: Nkx2-5^{em1Cin(IRES-iCre)}
• Gene: Nkx2-5 Location: Chr17:27057638-27063962 bp, - strand Genetic Position: Chr17, 13.6 cM
• Alliance: Nkx2-5^em1(icre)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Nkx2-5^em1(icre)Gpt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nkx2-5 (MGI:97350)

• CRISPR-targeting inserted an improved cre recombinase gene (icre). (J:293217)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx2-5 (mouse) Summary of all recombinase alleles driven by Nkx2-5. Alliance mouse Nkx2-5 gene page

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx2-5 Mutation: 21 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)