Sox2^em1(icre)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sox2^em1(icre)Gpt
• Name: SRY (sex determining region Y)-box 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7306644
• Synonyms: Sox2^{em1Cin(rox-stop-rox-P2A-iCre)}
• Gene: Sox2 Location: Chr3:34704554-34706610 bp, + strand Genetic Position: Chr3, 16.93 cM, cytoband A2-B
• Alliance: Sox2^em1(icre)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Sox2^em1(icre)Gpt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox2 (MGI:98364)

• Mutation details: CRISPR-targeting inserted at the stop codon a rox-flanked STOP cassette, P2A, and improved cre recombinase gene (icre). (J:293217)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox2 (mouse) Summary of all recombinase alleles driven by Sox2. Alliance mouse Sox2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox2 Mutation: 56 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)