Trp53^em3Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trp53^em3Gpt
• Name: transformation related protein 53; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
• MGI ID: MGI:7307968
• Synonyms: Trp53^{em1Cin(LSL-R172H)}
• Gene: Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
• Alliance: Trp53^em3Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Epitope tag)
• Mutations: Insertion, Single point mutation
• Mutation details: CRISPR-targeting inserted a floxed STOP cassette into intron 1 and the mutation producing the amino acid substitution of arginine with hsitidine at position 172 (R172H). (J:293217)
• Inheritance: Not Specified

Tumor Data

List all tumor models in MMHCdb carrying Trp53^em3Gpt

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp53 Mutation: 239 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)