Ywhab^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ywhab^em1Gpt
• Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7308745
• Synonyms: Ywhab^em1Cflox, Ywhab f
• Gene: Ywhab Location: Chr2:163837082-163860508 bp, + strand Genetic Position: Chr2, 84.59 cM, cytoband H3
• Alliance: Ywhab^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 3. (J:293217)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ywhab Mutation: 29 strains or lines available

References

• Original: J:323777 Ji L, et al., The 14-3-3 protein YWHAB inhibits glucagon-induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1. FEBS Lett. 2021 May;595(9):1275-1288
• All: 2 reference(s)