Zng1^em1Skan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zng1^em1Skan
• Name: Zn regulated GTPase metalloprotein activator 1; endonuclease-mediated mutation 1, Shoichiro Kanda
• MGI ID: MGI:7309144
• Gene: Zng1 Location: Chr19:24897280-24938974 bp, - strand Genetic Position: Chr19, 19.86 cM
• Alliance: Zng1^em1Skan page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR/Cas9 technology targeting exon 1 generated a 2 bp deletion and 109 bp insertion. (J:326010)

Disease models

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zng1 Mutation: 24 strains or lines available

References

• Original: J:326010 Kanda S, et al., Deletion in the Cobalamin Synthetase W Domain-Containing Protein 1 Gene Is associated with Congenital Anomalies of the Kidney and Urinary Tract. J Am Soc Nephrol. 2020 Jan;31(1):139-147
• All: 1 reference(s)