Angel2^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Angel2^em1Gpt
• Name: angel homolog 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7309788
• Synonyms: Angel2^em1Cd32, MmAngel2^KO
• Gene: Angel2 Location: Chr1:190657309-190679159 bp, + strand Genetic Position: Chr1, 96.28 cM
• Alliance: Angel2^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6NGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting introduced a coding region modification (del32). Exon 3 targeting led to a significant reduction of mRNA expression levels in the heart and liver of homozygous mutant mice. (J:293217, J:332461)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angel2 Mutation: 25 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)