Cldn17^em#Prso
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cldn17^em#Prso
• Name: claudin 17; endonuclease-mediated mutation, Payaningal R Somanath
• MGI ID: MGI:7309978
• Gene: Cldn17 Location: Chr16:88302695-88303866 bp, - strand Genetic Position: Chr16, 51.12 cM
• Alliance: Cldn17^em#Prso page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated small deletions (1bp-200bp). This record represents pooled data or data where the line number is not specified. (J:325994)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cldn17 Mutation: 9 strains or lines available

References

• Original: J:325994 Adil MS, et al., Claudin-17 Deficiency in Mice Results in Kidney Injury Due to Electrolyte Imbalance and Oxidative Stress. Cells. 2022 May 29;11(11)
• All: 1 reference(s)