Plppr5^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plppr5^em2Gpt
• Name: phospholipid phosphatase related 5; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7310260
• Gene: Plppr5 Location: Chr3:117368274-117483157 bp, + strand Genetic Position: Chr3, 51.21 cM, cytoband G2
• Alliance: Plppr5^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a 68.7Kb deletion of exons 2 through 6. (J:324004)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plppr5 Mutation: 20 strains or lines available

References

• Original: J:324004 Sun Y, et al., Effects of Melatonin on Neurobehavior and Cognition in a Cerebral Palsy Model of plppr5-/- Mice. Front Endocrinol (Lausanne). 2021;12:598788
• All: 4 reference(s)