Mettl13^tm1Kmgen
Targeted Allele Detail

Summary

• Symbol: Mettl13^tm1Kmgen
• Name: methyltransferase 13, eEF1A lysine and N-terminal methyltransferase; targeted mutation 1, Medical Institute of Bioregulation, Kyushu University
• MGI ID: MGI:7310345
• Gene: Mettl13 Location: Chr1:162359694-162376098 bp, - strand Genetic Position: Chr1, 70.29 cM, cytoband H1
• Alliance: Mettl13^tm1Kmgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319655
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exon 2 with a neomycin resistance cassette. (J:319655)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mettl13 Mutation: 32 strains or lines available

References

• Original: J:319655 Li Y, et al., FEAT enhances INSL3 expression in testicular Leydig cells. Genes Cells. 2018 Nov;23(11):952-962
• All: 1 reference(s)