Cemip^tm1.1Okda
Targeted Allele Detail

Summary

• Symbol: Cemip^tm1.1Okda
• Name: cell migration inducing protein, hyaluronan binding; targeted mutation 1.1, Yasunori Okada
• MGI ID: MGI:7311628
• Gene: Cemip Location: Chr7:83582065-83735710 bp, - strand Genetic Position: Chr7, 48.35 cM, cytoband D3
• Alliance: Cemip^tm1.1Okda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241936
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted a floxed neomycin resistance cassette with a 5 prime loxP site upstream of exon 1 and a single loxP site downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. (J:241936)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cemip Mutation: 67 strains or lines available

References

• Original: J:241936 Shimoda M, et al., Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Controls Endochondral Ossification through Hyaluronan Metabolism. Am J Pathol. 2017 May;187(5):1162-1176
• All: 5 reference(s)