Irgc^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Irgc^em1Osb
• Name: immunity related GTPase cinema; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7311754
• Gene: Irgc Location: Chr7:24131344-24145107 bp, - strand Genetic Position: Chr7, 10.74 cM
• Alliance: Irgc^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of the coding region deleted 1266 bp. (J:326368)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irgc Mutation: 17 strains or lines available

References

• Original: J:326368 Kaneda Y, et al., IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice. Dev Biol. 2022 Aug;488:104-113
• All: 1 reference(s)