Ppp4r3a^em1Qili
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp4r3a^em1Qili
• Name: protein phosphatase 4 regulatory subunit 3A; endonuclease-mediated mutation 1, Qiji Liu
• MGI ID: MGI:7312039
• Synonyms: Ppp4r3a^flox
• Gene: Ppp4r3a Location: Chr12:101005668-101049961 bp, - strand Genetic Position: Chr12, 51.17 cM
• Alliance: Ppp4r3a^em1Qili page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR-targeting introduced a loxP site upstream of exon 2 and a Rox-flanked neomycin resistance cassette with a 3' loxP site downstream of exon 2. (J:326388)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp4r3a Mutation: 68 strains or lines available

References

• Original: J:326388 Gao F, et al., Ppp4r3a deficiency leads to depression-like behaviors in mice by modulating the synthesis of synaptic proteins. Dis Model Mech. 2022 Jun 1;15(6):dmm049374
• All: 1 reference(s)