Actrt1^em1Chnsr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Actrt1^em1Chnsr
• Name: actin-related protein T1; endonuclease-mediated mutation 1, Su-Ren Chen
• MGI ID: MGI:7312068
• Gene: Actrt1 Location: ChrX:45417884-45419222 bp, + strand Genetic Position: ChrX, 24.54 cM, cytoband A3.1
• Alliance: Actrt1^em1Chnsr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the coding exon. (J:326444)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Actrt1 Mutation: 4 strains or lines available

References

• Original: J:326444 Zhang XZ, et al., Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice. Development. 2022 Jun 15;149(12):dev200489
• All: 1 reference(s)