Fstl1^{tm2.1(cre/ERT2)Ning}
Targeted Allele Detail

Summary

• Symbol: Fstl1^{tm2.1(cre/ERT2)Ning}
• Name: follistatin-like 1; targeted mutation 2.1, Wen Ning
• MGI ID: MGI:7314239
• Synonyms: Fstl1-CreERT2
• Gene: Fstl1 Location: Chr16:37597417-37656878 bp, + strand Genetic Position: Chr16, 26.48 cM
• Alliance: Fstl1^{tm2.1(cre/ERT2)Ning} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317614
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Fstl1^{tm2.1(cre/ERT2)Ning} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fstl1 (MGI:102793)

• Mutation details: The targeting construct introduced the P2A-CreERT2 cassette in frame followed by an FRT-flanked neomycin cassette before the stop codon TAA in the exon 11 of the Fstl1 gene. The FRT-flanked neomycin cassette was removed by crossing to flp deleter. (J:317614)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fstl1 (mouse) Summary of all recombinase alleles driven by Fstl1. Comparative matrix view of recombinase activities Alliance mouse Fstl1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fstl1 Mutation: 46 strains or lines available

References

• Original: J:317614 Liu X, et al., Cell type specific expression of Follistatin-like 1 (Fstl1) in mouse embryonic lung development. J Mol Histol. 2018 Aug;49(4):399-409
• All: 2 reference(s)