Sfrp1^{tm1(cre/ERT2)Hmd}
Targeted Allele Detail

Summary

• Symbol: Sfrp1^{tm1(cre/ERT2)Hmd}
• Name: secreted frizzled-related protein 1; targeted mutation 1, Hiroshi Hamada
• MGI ID: MGI:7314301
• Synonyms: Sfrp1-Cre^ERT2
• Gene: Sfrp1 Location: Chr8:23901518-23939648 bp, + strand Genetic Position: Chr8, 11.48 cM
• Alliance: Sfrp1^{tm1(cre/ERT2)Hmd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240026
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Sfrp1^{tm1(cre/ERT2)Hmd} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sfrp1 (MGI:892014)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sfrp1 (mouse) Summary of all recombinase alleles driven by Sfrp1. Alliance mouse Sfrp1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfrp1 Mutation: 19 strains or lines available

References

• Original: J:240026 Minegishi K, et al., A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 Mar 13;40(5):439-452.e4
• All: 1 reference(s)