Bend2^em1Hncs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bend2^em1Hncs
• Name: BEN domain containing 2; endonuclease-mediated mutation 1, Chunsheng Han
• MGI ID: MGI:7314760
• Synonyms: Bend2^-4k
• Gene: Bend2 Location: ChrX:160080852-160124208 bp, + strand Genetic Position: ChrX, 73.95 cM
• Alliance: Bend2^em1Hncs page

Mutation origin

• Strain of Origin: C57BL/6J and DBA/2J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed 4 kb consisting of exons 12 and 13. (J:325496)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bend2 Mutation: 0 strains or lines available

References

• Original: J:325496 Ma L, et al., Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis. Sci Adv. 2022 May 27;8(21):eabn1606
• All: 1 reference(s)